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Unlocking Recovery: NAD+ and Glutathione Treatments for Long COVID Relief

In the wake of the global COVID-19 pandemic, a new challenge has emerged, affecting millions worldwide: long COVID. Characterized by a cluster of lingering symptoms that continue for months after the initial infection has cleared, long COVID can drastically reduce the quality of life, impacting daily activities and overall well-being. 

As the medical community seeks effective treatments for these persistent and often debilitating symptoms, two promising molecules have come to the forefront: NAD+ (Nicotinamide Adenine Dinucleotide) and glutathione. These substances, pivotal for cellular health and antioxidant defense, offer hope in the battle against the long-term effects of COVID-19.

At Performance Hyperbaric, we understand the urgency of finding solutions for those suffering from long COVID. With a commitment to innovative care, we offer NAD+ and glutathione treatments, administered via IV or IM injections, designed to support recovery and enhance well-being. 

This article aims to shed light on how these treatments can play a crucial role in overcoming long COVID symptoms, backed by scientific insights and our expertise in delivering these therapies. Join us in exploring the potential of NAD+ and glutathione in paving the path to recovery, and discover how our tailored treatments at Performance Hyperbaric can help you regain control over your health.

NAD+ can help with long-covid.
NAD+ can help with brain fog associated with long-covid.

Understanding Long COVID

Long COVID, also known as Post-Acute Sequelae of SARS-CoV-2 infection (PASC), has emerged as a perplexing and debilitating condition affecting millions globally. Characterized by a wide array of symptoms that persist for months or even years after the acute phase of the infection has resolved, long COVID can significantly impact the quality of life of those affected. Symptoms range from persistent fatigue, brain fog, and shortness of breath to more severe complications such as cardiovascular issues and multisystem inflammatory syndromes.

Studies suggest that a significant portion of COVID-19 survivors experience some form of long COVID, with symptoms persisting well beyond the initial recovery period. A recent study found that one out of every five people who recovered from COVID-19 reported experiencing what's known as Long COVID. This condition involves lingering symptoms that persist long after the initial infection has cleared up. The most common complaints among these individuals were fatigue, difficulties with concentration (often described as "brain fog"), depression, anxiety, and trouble sleeping. Interestingly, the study also discovered that females were 58% more likely to experience Long COVID compared to males. This suggests that certain factors, such as gender, might influence who is more susceptible to this prolonged form of illness after recovering from COVID-19.

The exact cause of long COVID remains under investigation, but several theories have been proposed, including persistent viral reservoirs, immune dysregulation, and ongoing inflammatory responses. This complexity and the broad spectrum of symptoms make managing and treating long COVID particularly challenging, underscoring the need for innovative approaches and therapies.

In this context, therapies that support cellular health and immune function, such as NAD+ and glutathione supplementation, offer promising avenues for relief and recovery. By targeting underlying mechanisms such as cellular repair and oxidative stress reduction, these treatments aim to alleviate symptoms and improve the overall health and well-being of long COVID sufferers.

As the medical community continues to unravel the mysteries of long COVID, it is crucial to explore all potential therapeutic options. Treatments like NAD+ and glutathione, administered under professional supervision, such as those offered at Performance Hyperbaric, represent a beacon of hope for many grappling with the long-term effects of COVID-19.

Spotlight on NAD+

Nicotinamide adenine dinucleotide (NAD+) is a coenzyme present in all living cells that plays a crucial role in metabolic processes and cellular health. Its primary function is to facilitate the transfer of electrons in the mitochondria, the powerhouse of the cell, thereby playing a pivotal role in energy production. Beyond its critical involvement in metabolism, NAD+ also contributes to DNA repair, maintains cellular health, and regulates immune function—key areas of concern for those recovering from illnesses like COVID-19.

Research has illuminated the link between NAD+ levels and immune health, showing that adequate NAD+ is essential for the proper functioning of the immune system. This connection is particularly relevant for long COVID sufferers, as the condition is often characterized by ongoing immune system challenges and chronic inflammation. 

A recent study highlights the importance of NAD+ metabolism in regulating the behavior of both innate and adaptive immune cells, which are crucial players in our body's defense system. By influencing NAD+ levels, we can potentially alter the way these immune cells function, impacting the severity and course of inflammatory responses. This suggests that manipulating NAD+ availability could have significant implications for managing immunological diseases. For long COVID survivors, whose immune systems may be dysregulated and prone to prolonged inflammation, understanding and potentially modulating NAD+ metabolism could offer new avenues for intervention and treatment to alleviate symptoms and improve recovery.

Studies have indicated that NAD+ levels tend to decline with age and under conditions of metabolic stress, which can exacerbate the symptoms of viral infections and hinder recovery.

The therapeutic potential of NAD+ supplementation lies in its ability to replenish cellular NAD+ levels, thereby supporting the body’s natural healing processes. Supplementation can enhance energy metabolism, promote cellular repair, and support immune function—key factors in the recovery from long COVID. By restoring NAD+ levels, patients may experience improvements in energy, cognitive function, and overall resilience against ongoing symptoms.

A recent study investigated the potential of fasting as a therapeutic approach to aid in the recovery from COVID-19. While pharmacological therapies are crucial, non-pharmacological interventions like fasting have gained attention for their potential health benefits. Researchers found evidence suggesting that fasting could enhance recovery from COVID-19 by increasing levels of nicotinamide adenine dinucleotide (NAD+), a molecule important for cellular function. They highlighted that fasting might help prevent SARS-CoV-2 infection and accelerate recovery from the virus. Additionally, the study proposed that supplementing NAD+ could be pivotal for long COVID patients, potentially alleviating symptoms and aiding in recovery. These findings underscore the importance of further research into the role of fasting and NAD+ supplementation in combating COVID-19 and its long-term effects.

At Performance Hyperbaric, we recognize the critical role of NAD+ in recovery and offer it via intravenous (IV) or intramuscular (IM) injections. This method of delivery ensures that NAD+ is directly available to the body's cells, bypassing the digestive system and facilitating immediate utilization. Such targeted administration can significantly impact recovery trajectories for those battling the persistent effects of long COVID.

The promise of NAD+ therapy extends beyond mere symptom management. By addressing one of the underlying issues of cellular dysfunction, NAD+ supplementation offers a pathway to not just coping, but potentially thriving in the aftermath of a COVID-19 infection. Through our carefully administered treatments, Performance Hyperbaric aims to harness this potential, offering patients a scientifically grounded option for support and recovery in their journey beyond COVID-19.

The Power of Glutathione

Glutathione, often heralded as the body's 'master antioxidant,' is a tripeptide composed of three amino acids: cysteine, glutamate, and glycine. It plays a critical role in protecting the body against oxidative stress, detoxifying harmful substances, supporting immune function, and maintaining overall cellular health. Given its widespread benefits, glutathione is a key player in the body's defense system, particularly in the lungs and other respiratory tissues, where it can neutralize free radicals and other harmful agents.

Oxidative stress is a common thread linking many of the symptoms and underlying mechanisms of long COVID. This condition is characterized by an imbalance between free radicals (unstable molecules that can damage cells) and antioxidants like glutathione that neutralize them. Elevated levels of oxidative stress have been observed in individuals with long COVID, contributing to inflammation, tissue damage, and the broad spectrum of symptoms associated with the syndrome. 

A study published in the Journal of Molecular Psychiatry in 2023 explored the link between the immune response during the acute phase of COVID-19 and the severity of long-term symptoms like chronic fatigue, depression, and anxiety. Researchers examined factors like body temperature and oxygen levels during acute infection and their effects on immune and stress pathways, as well as neuropsychiatric symptoms in individuals with long COVID. They found that about a third of the long COVID patients had significant abnormalities in oxygen levels, body temperature, and markers of oxidative stress and antioxidant defenses. These abnormalities strongly correlated with increased depression, anxiety, and fatigue symptoms. Specifically, they observed that elevated oxidative stress, indicated by markers like malondialdehyde and myeloperoxidase, played a significant role in contributing to the symptoms of long COVID. This suggests that oxidative stress may be a key factor driving inflammation and tissue damage in long COVID, leading to the diverse range of symptoms experienced by individuals with the syndrome.

Supplementing with glutathione may offer significant benefits for patients suffering from long COVID by directly addressing oxidative stress and inflammation. Studies have shown that elevated glutathione levels can enhance the antioxidant defense system, support detoxification processes, and improve immune response. For individuals experiencing long-term effects of COVID-19, glutathione supplementation could potentially alleviate symptoms like fatigue, brain fog, and respiratory discomfort by reducing oxidative damage and supporting cellular repair.

At Performance Hyperbaric, glutathione is administered directly through IV or IM injections, ensuring that this potent antioxidant is delivered efficiently to where it's most needed in the body. This method of administration bypasses the digestive system, which can degrade glutathione, ensuring maximal absorption and utilization by the body's cells. Our targeted approach aims to replenish glutathione levels effectively, offering our patients a powerful tool in their recovery from long COVID.

The administration of glutathione at Performance Hyperbaric is designed not just to alleviate symptoms but to address one of the root causes of long COVID discomfort—oxidative stress. By bolstering the body's antioxidant defenses, our treatments aim to support healing at a cellular level, offering a path towards improved well-being and quality of life for our patients. In the battle against the lingering effects of COVID-19, glutathione represents a beacon of hope, potentially easing the journey towards recovery and better health.

Treatment at Performance Hyperbaric

At Performance Hyperbaric, we understand that recovery from long COVID requires a multifaceted approach. That’s why we offer targeted treatments with NAD+ and glutathione—two powerful agents that have shown promise in supporting recovery from long-term COVID-19 symptoms. 

Here's a closer look at what patients can expect when they come to us for treatment:

Tailored Treatment Plans

We begin with a comprehensive evaluation to understand each patient's unique health profile and long COVID symptoms. This personalized approach ensures that our treatment plans are tailored to meet the specific needs of each individual, optimizing the potential for recovery and health improvement.

Professional Administration of NAD+ and Glutathione

Our clinic specializes in the professional administration of NAD+ and glutathione through IV or IM injections. This method ensures direct delivery into the bloodstream, bypassing the digestive system for maximum absorption and effectiveness. Our trained medical staff oversees every treatment, ensuring safety and comfort throughout the process.

The IV and IM Injection Process

  • IV Therapy: Intravenous (IV) therapy allows for NAD+ and glutathione to be infused directly into the vein, providing immediate availability to the body’s cells. This method is particularly effective for comprehensive absorption and offers the advantage of adjusting dosages according to individual tolerance and response.

  • IM Injections: Intramuscular (IM) injections deliver NAD+ and glutathione into a muscle, from where they are gradually absorbed into the bloodstream. This method can be a quicker and less invasive option, suitable for those who may prefer it over IV therapy.

A Supportive Environment

We provide a comfortable and supportive setting for our treatments, understanding that recovery from long COVID can be a challenging journey. Our clinic is designed to be a haven where patients can relax as they receive their treatments, with staff available to answer questions and provide assistance throughout the process.

Ongoing Care and Support

Our commitment to our patients extends beyond the treatment sessions. We offer ongoing support and follow-up to monitor progress, adjust treatments as needed, and provide guidance on complementary lifestyle changes that can support recovery. Our goal is to empower our patients on their path to improved health and wellness.

Why Choose Performance Hyperbaric for NAD+ and Glutathione Treatment?

Opting for treatment at Performance Hyperbaric means choosing a partner committed to your recovery from long COVID. Our use of scientifically backed therapies, combined with a personalized and patient-centered approach, sets us apart. We believe in the power of NAD+ and glutathione to not only alleviate long COVID symptoms but also to enhance overall well-being, making them integral components of our treatment offerings.

Recovery from long COVID is a journey, and Performance Hyperbaric is here to support you every step of the way. With our targeted treatments, professional care, and supportive environment, we are dedicated to helping our patients regain their health and vitality.

Safety and Considerations

When considering treatments like NAD+ and glutathione, particularly for conditions as complex and varied as long COVID, understanding their safety profile and any considerations is crucial. At Performance Hyperbaric, we prioritize the well-being and health of our patients by adhering to rigorous safety standards and providing comprehensive information to ensure informed decisions.

Safety Profile of NAD+ and Glutathione

NAD+ and glutathione have been extensively researched and are known for their safety when administered under professional supervision. These compounds are naturally occurring in the body, playing essential roles in cellular processes and antioxidant defense. However, like any treatment, they come with considerations that are carefully managed in a clinical setting:

  • Allergic Reactions: While rare, there is always a possibility of an allergic reaction to any substance introduced into the body. Our clinic is equipped to manage such reactions immediately and effectively.

  • Side Effects: Some patients might experience mild side effects from IV or IM treatments, such as discomfort at the injection site, fatigue, or feeling flush. These symptoms are typically temporary and subside on their own.

  • Dosage and Administration: Determining the correct dosage and method of administration is essential for the efficacy and safety of NAD+ and glutathione treatments. Our healthcare professionals assess each patient’s specific needs to customize treatment plans accordingly.

Professional Supervision and Individual Assessment

Before initiating any treatment, Performance Hyperbaric conducts a thorough assessment to determine suitability and tailor the therapy to individual health profiles. This personalized approach ensures that treatments are not only effective but also aligned with each patient’s unique needs and circumstances.

  • Pre-Treatment Evaluation: Includes a detailed medical history, assessment of long COVID symptoms, and any underlying health conditions that could influence treatment efficacy or safety.

  • Monitoring During Treatment: Continuous monitoring by our trained medical staff during IV or IM administration ensures any adverse reactions are promptly addressed, and patient comfort is maintained.

  • Post-Treatment Follow-up: Follow-up care is a critical component of our treatment protocol, allowing us to assess treatment efficacy, address any concerns, and adjust future treatments as needed.

Making an Informed Decision

Choosing to pursue treatment with NAD+ and glutathione is a significant decision, particularly for individuals grappling with the persistent and often debilitating effects of long COVID. At Performance Hyperbaric, we believe in empowering our patients with comprehensive information and support to make informed health decisions. Our team is always available to discuss potential benefits, address concerns, and provide the insights needed to understand how these treatments may fit into your overall recovery strategy.

We are committed to transparency, safety, and excellence in care, ensuring that every patient feels confident and informed throughout their treatment journey. As we continue to navigate the challenges of long COVID together, Performance Hyperbaric stands as a dedicated partner in health, offering innovative treatments grounded in safety and compassion.


The journey through long COVID is a path marked by uncertainty, with each patient experiencing a unique set of challenges and symptoms that can profoundly affect their quality of life. In this landscape of ongoing research and exploration for effective treatments, NAD+ and glutathione emerge as beacons of hope—offering a scientific basis for potential relief and recovery. At Performance Hyperbaric, we are at the forefront of utilizing these powerful therapies to support individuals battling the lingering effects of COVID-19.

Our commitment extends beyond providing cutting-edge treatments; we are dedicated to offering a sanctuary for healing, where each patient is treated with the utmost care and personalized attention. The administration of NAD+ and glutathione in our clinic is more than a medical procedure; it's a step towards reclaiming the vitality and wellness lost to long COVID. By addressing the root causes of long COVID symptoms, such as cellular dysfunction and oxidative stress, our treatments aim to restore balance and promote recovery at a foundational level.

Choosing Performance Hyperbaric means opting for a partner who understands the complexities of long COVID and is committed to exploring all avenues to support your recovery journey. With our focus on safety, individualized care, and the therapeutic potential of NAD+ and glutathione, we offer a hopeful pathway for those seeking to overcome the challenges of long COVID.

We invite you to reach out, learn more, and discover how our specialized treatments can be a part of your recovery journey. Together, we can work towards a future where the impacts of long COVID are not just managed but overcome, restoring health, vitality, and hope for all those affected.

Call us at 772-241-2763 to find our specials and promotions! We can work with your schedule and can create a custom plan designed to reach your health and wellness goals!

If you or a loved one are navigating the complexities of long COVID and are seeking effective, compassionate care, Performance Hyperbaric is here to help. Contact us today to learn more about our NAD+ and glutathione treatments, and let us guide you through a personalized consultation to determine how we can support your path to recovery. Don't let long COVID define your health journey—discover how targeted therapies at Performance Hyperbaric can make a difference. Together, we can take the next step towards healing and wellness.


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  5. Stufano, A., Isgrò, C., Palese, L. L., Caretta, P., De Maria, L., Lovreglio, P., & Sardanelli, A. M. (2023). Oxidative Damage and Post-COVID Syndrome: A Cross-Sectional Study in a Cohort of Italian Workers. International journal of molecular sciences, 24(8), 7445.

  6. Al-Hakeim, H. K., Al-Rubaye, H. T., Al-Hadrawi, D. S., Almulla, A. F., & Maes, M. (2023). Long-COVID post-viral chronic fatigue and affective symptoms are associated with oxidative damage, lowered antioxidant defenses and inflammation: a proof of concept and mechanism study. Molecular psychiatry, 28(2), 564–578.

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